Hi and welcome
Offtopic: I assume you have a serious backup strategie
Here are the insights.
Absolutely. Although you can resume an already started vault migration, I have seen several reports in this board where user couldn’t perform a successful migration with on demand files. Not just because operation limitations, but also because files were not available and so on. On the other hand I think there were gdrive reports of successful migration with on demand files (cannot proof it right now). So I think there is a chance that you finish the migration of such an amount of data after a long time of resumeing the process and up-/downloading files. But I’m pretty sure you will have no fun.
From my point of view and in your case I recommend a local migration.
Disclaimer and update: this is for gdrive. iCloud users for example have to do the migration local. I stay with my general recommendation: migrate your vaults local